The effect of bioactive glass particle size and liquid phase on the physical-chemical and mechanical properties of carbonated apatite cement

This study reports for the first time effect of particle size bioactive glass 46S6 on physico-chemical and mechanical properties carbonated apatite cement (CPC) composed brushite (CaHPO4. H2O) vaterite (CaCO3). Three ranges were investigated: coarse (BGc: 100–200 ?m), medium (BGm: 40–100 fine (BGf<40 ?m). For composite formulations, three liquid phases used: distilled water as a simple setting solution, sodium alginate hydrogel cohesion injectability enhancer, solubilized in accelerator (Na2HPO4) solution (Alg-NaP) to control time. The changes bioglass phase lead clear modifications setting, rheological, prepared cements. optimization different parameters reveals that formulation with BGc Alg-NaP provides best properties: good 95%, excellent cohesion, 10 min meets range required by clinicians, strength 10.5 MPa comparable cancellous bone.